Dialysis system having enhanced features including drip prevention

A peritoneal dialysis (“PD”) machine comprising:

• a housing;
• a PD fluid pump housed by the housing;
• a reusable patient line extending from the housing, the reusable patient line including a distal end configured to be connected so that the reusable patient line is placed in fluid communication with at least one internal PD fluid line located within the housing;
• at least one reusable PD fluid line extending from the housing, the at least one reusable PD fluid line including a distal end configured to be connected so that the at least one PD fluid line is placed in fluid communication with the at least one internal PD fluid line;
• and
• a control unit configured to cause, prior to any of the lines being connected for treatment, the PD fluid pump to apply a negative pressure to at least one of the reusable patient line or the at least one reusable PD fluid line when connected for fluid communication with the at least one internal PD fluid line.