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US 2023/0414784 A1Published application
Cationic Bottlebrush Polymers for Gene Delivery
AssigneeRegents of the University of Minnesota
InventorsTheresa REINEKE, Rishad DALAL
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Abstract
An example compound includes a bottlebrush polymer associated with a biological agent. The bottlebrush polymer may include a backbone and a plurality of side-chains covalently bonded to the backbone. Each side-chain of the plurality of side-chains may include a plurality of repeating cationic units.
Claims20
A compound comprising:
- a bottlebrush unimolecular polymer comprising:
- a backbone;
- and
- a plurality of side-chains covalently bonded to the backbone, wherein each side-chain of the plurality of side-chains comprises a plurality of repeating cationic units.
1 more element
A compound comprising:
- a bottlebrush unimolecular polymer comprising:
- a backbone;
- and
- a plurality of side-chains covalently bonded to the backbone, wherein each side-chain of the plurality of side-chains comprises a repeating cationic unit;
- and
- a biological agent associated with the bottlebrush unimolecular polymer.
3 more elements
A method, comprising:
- synthesizing a bottlebrush unimolecular polymer comprising:
- a backbone;
- and
- a plurality of side-chains covalently bonded to the backbone, wherein each side-chain of the plurality of side-chains comprises a repeating cationic unit;
- and
- associating the bottlebrush unimolecular polymer with a biomacromolecule to form a bottleplex.
3 more elements
Dependencies are inferred from the claim text.