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US 2023/0414767 A1Published application
Methods And Compositions For The Treatment Of Cancer
AssigneeSouth Dakota Board of Regents
InventorsKhosrow Rezvani, Grigoriy Sereda
Life of this patent
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Abstract
Disclosed herein are compositions for treating cancer comprising a modified veratridine. In certain aspects, the modified veratridine comprises a polyglutamic acid (PLE) or polyethylene glycol/polyglutamic acid (PEG-PLE) conjugated to the 4′ hemiketal thereof. Further disclosed is a method of treating colorectal cancer in a subject comprising administering to a subject an effective amount of the disclosed compositions.
Claims1
A composition for treating cancer, comprising a compound having the structure:
- and a modification moiety of polyglutamic acid (PLE) or polyethylene glycol/polyglutamic acid (PEG-PLE) conjugated to the 4′ hemiketal thereof.
Dependencies are inferred from the claim text.