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US 2023/0414682 A1Published application
Methods for Treating a Health Condition with Probiotics
OwnerSabine Hazaninventor
Life of this patent
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Abstract
Methods of treating a health condition by standardizing patients and donors with pre-treatment protocols to enhance the effects of probiotic administration, improving preservation steps of samples handled, and selecting best matching donors for selection for probiotic administration to effectively treat the health condition.
Claims22
A method of treating a patient with a health condition, the method comprising the steps of:
- a) screening an individual to determine whether the individual has the health condition, wherein if the individual has the health condition, the individual is the patient;
- b) preparing the patient for a fecal microbiota transplant by directing discontinuation of any existing antibiotic treatment;
- c) acquiring a fecal sample from the patient, wherein the fecal sample contains a microbiome of the patient;
- d) processing the fecal samples from the patient by extracting and purifying DNA from the fecal sample of the patient and preparing a DNA library of the microbiome of the patient;
- e) preparing a plurality of donors for the fecal microbiota transplant by directing discontinuation of any existing antibiotic treatment;
- f) acquiring fecal samples from the plurality of donors, wherein the fecal samples of the plurality of donors contain a microbiome of the respective donor;
- g) processing the fecal samples from the plurality of donors to by extracting and purifying DNA from the fecal samples of the donor and preparing a separate DNA library of the microbiomes of each donor;
- h) comparing the DNA library from the patient to the DNA library of each donor to determine a matching donor having a DNA library that is more similar to the DNA library of the patient as compared to the DNA library of other donors in the plurality of donors;
- and
- i) administering rectally into the patient a probiotic derived from the matching donor, wherein the probiotic treats the health condition of the patient.
7 more elements
A method of treating a patient with a health condition, the method comprising the steps of:
- a) screening an individual to determine whether the individual has the health condition, wherein if the individual has the health condition, the individual is the patient;
- b) preparing the patient for a probiotic administration by directing discontinuation of any existing antibiotic treatment;
- c) acquiring a fecal sample from the patient, wherein the fecal sample contains a microbiome of the patient;
- d) processing the fecal samples from the patient by extracting and purifying DNA from the fecal sample of the patient and preparing a DNA library of the microbiome of the patient;
- e) preparing a plurality of donors for the probiotic administration by directing discontinuation of any existing antibiotic treatment;
- f) acquiring fecal samples from the plurality of donors, wherein the fecal samples of the plurality of donors contain a microbiome of the respective donor;
- g) processing the fecal samples from the plurality of donors to by extracting and purifying DNA from the fecal samples of the donor and preparing a separate DNA library of the microbiomes of each donor;
- h) comparing the DNA library from the patient to the DNA library of each donor to determine a matching donor having a DNA library that is more similar to the DNA library of the patient as compared to the DNA library of other donors in the plurality of donors;
- and
- i) administering a probiotic derived from the matching donor, wherein the probiotic treats the health condition of the patient.
7 more elements
Dependencies are inferred from the claim text.