Methods for treating acute myeloid leukemia and related conditions
AssigneeGlycoMimetics, Inc.
InventorsHelen M. THACKRAY, Henry H. FLANNER, Curt D. WOLFGANG
Life of this patent
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Abstract
Methods for treating or inhibiting cancer and/or one or more related conditions by administering to a subject in need thereof an effective amount of a compound of Formula (I) a prodrug thereof or a pharmaceutically acceptable salt of any of the foregoing. For example, methods for treating AML, MDS, neutropenia, and/or mucositis comprising administering a pharmaceutical composition comprising a compound of Formula (I) are described.
Claims38
1-24. (canceled)
A method for reducing or preventing at least one side effect resulting from at least one of chemotherapy and radiotherapy in preparation for stem cell or bone marrow transplantation in a subject, the method comprising administering to the subject at least one compound chosen from a compound of Formula (I):
- and pharmaceutically acceptable salts thereof;
- wherein the at least one compound is administered to the subject prior to, simultaneously with, or shortly after administration of at least one of chemotherapy and radiotherapy to the subject;
- and
- wherein the subject is thereafter administered at least one of stem cell transplantation or bone marrow transplantation.
Dependencies are inferred from the claim text.