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US 2023/0414588 A1Published application
Compositions and methods for treating patients with amyotrophic lateral sclerosis (als)
AssigneeCuraSen Therapeutics, Inc.
InventorAnthony P. Ford
Life of this patent
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Abstract
In various aspects and embodiments provided are compositions and methods for treating a patient that has ALS (or Lou Gehrig's disease or motor neuron disease). More specifically, the disclosure in some embodiments includes administration of a β-AR agonist (such as a β-agent) and optionally a peripherally acting β-blocker (PABRA) to a patient in need thereof.
Claims44
A method comprising:
- administering to a patient a β-AR agonist and optionally a peripherally acting β-blocker (PABRA), wherein the peripherally acting β-blocker (PABRA) is administered in a sub-therapeutic dose, wherein the patient has amyotrophic lateral sclerosis (ALS).
A method, comprising:
- subjecting an ALS patient to a test to determine cognitive function and/or to identify whether said patient is in need of or desiring improvement of cognitive function;
- identifying a status of ALS based on a spatial pattern of the test result;
- and subsequently administering to said patient a pharmaceutical composition comprising a β-AR agonist, wherein the peripherally acting β-blocker (PABRA) is optional and administered optionally and in a sub-therapeutic dose.
Dependencies are inferred from the claim text.