Use of n-acetylcysteine to treat central nervous system disorders
AssigneesNeouronasal, Inc., Burke Neurological Institue
InventorsRajiv R. RATAN, Saravanan KARUPPAGOUNDER, Thomas I. BRADSHAW
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Abstract
The present disclosure describes methods of treating a central nervous system condition associated with oxidative stress using a 5-lipoxigenase activating protein (FLAP) inhibitor, for example, N-acetylcysteine or nordihydroguaiaretic acid. The present disclosure also describes methods of treating a central nervous system condition with N-acetylcysteine and a second therapeutic agent such as prostaglandin E2.
Claims20
1-21. (canceled)
A method of treating a condition, the method comprising administering to a subject in need thereof a therapeutically-effective amount of N-acetyl cysteine (NAC), wherein the administering is to a nasal cavity of the subject, wherein the condition:
- a) is Parkinson's disease;
- b) is associated with degeneration of the central nervous system of the subject;
- c) is a neuropsychiatric disorder;
- and
- d) is associated with oxidative stress.
Dependencies are inferred from the claim text.