Method for inhibiting asenapine degradation
AssigneeHisamitsu Pharmaceutical Co., Inc.
InventorsYuka TAKAGI, Nao IWAMOTO
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Abstract
Disclosed is a method for inhibiting degradation of asenapine or a pharmaceutically acceptable salt thereof in a patch. The patch comprises an adhesive layer on a base, and the adhesive layer contains an adhesive base and asenapine or a pharmaceutically acceptable salt thereof. The method includes incorporating at least one amine compound selected from the group consisting of monoethanolamine, diethanolamine, diisopropanolamine, isopropanolamine, triethanolamine and meglumine in the adhesive layer.
Claims9
1-4. (canceled)
A method for suppressing degradation of asenapine or a pharmaceutically acceptable salt thereof in a patch,
- wherein the patch comprises an adhesive layer on a backing, the adhesive layer comprises an adhesive base and asenapine or a pharmaceutically acceptable salt thereof, and
- comprising adding at least one amine compound selected from the group consisting of monoethanolamine, diethanolamine, diisopropanolamine, isopropanolamine, triethanolamine and meglumine in the adhesive layer.
Dependencies are inferred from the claim text.