Proteinoid compounds, process of preparing same and uses thereof
AssigneeBar-Ilan University
InventorsShlomo MARGEL, Michal KOLITZ DOMB, Stella KIEL, Elisheva SASON
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Abstract
Proteinoid compounds characterized by a molecular weight (Mw) of at least 15,000 Da, processes of preparing such compounds and methods of use thereof, are provided. A method of monitoring the presence and metastases of cancer in a body of an individual is further disclosed.
Claims17
A composition comprising proteinoid compounds in a form of self-assembled hollowsphere particles, wherein a hydrodynamic size of at least 80% of the self-assembled hollowsphere particles varies by less than 25% from an average hydrodynamic diameter of the entire self-assembled hollowsphere particles of the composition;
- wherein each of said proteinoid compounds is a random amino acid co-polymer, and wherein said proteinoid compounds are characterized by a dispersity index (1)) value of less than 1.3 and by a weight average molecular weight (Mw) of at least 15,000 Da;
- and wherein said random amino acid co-polymer is characterized by an IR spectrum devoid of a carbonyl stretching peak above 1700 cm−1.
Dependencies are inferred from the claim text.