Fibrin particles and methods of making the same
AssigneeNorth Carolina State University
InventorsIsmaeel MUHAMED, Ashley C. BROWN, Frances S. LIGLER
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Abstract
Disclosed herein are low density particles comprising polymerized fibrin that are micrometer or nanometer sized in diameter. The particles can further include at least one therapeutic agent. The particles may be used to treat wounds, by administration directly or systemically to the site of the wound. Exemplary wounds that may be treated with the fibrin particles include a trauma wound, a surgical wound, a burn wound, or an ulcer wound. Also disclosed herein are methods for preparing the particles using a shearing process.
Claims25
1-14. (canceled)
A method of preparing a fibrin particle, comprising shearing an aqueous composition comprising fibrin into particles.
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Dependencies are inferred from the claim text.