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US 2023/0414524 A1Published application
Double layered delayed-release hard capsules
AssigneeCapsugel Belgium NV
InventorsXiongwei He, Ljiljana Palangetic, Stefaan Vanquickenborne, Jerome Cuevas
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Abstract
The invention discloses double layered delayed-release hard capsules made by double dipping, that is by two consecutive dip molding steps on the same mold pin without removing the film, provided by the first dip molding step, from the mold pin between the two dip molding steps, but dipping the mold pin with this first film in the second dip molding step, each dip molding step is done with a different polymer melt, providing a double layered delayed-release capsule.
Claims21
1-31. (canceled)
A two piece hard capsule shell, wherein:
- the two piece hard capsule shell is prepared by a double dipping process;
- a wall of the two piece hard capsule shell comprises two layers of wall forming polymers, one inner layer and one outer layer on the inner layer;
- the wall forming polymer of the inner layer comprises a water soluble film forming polymer comprising HPMC;
- and
- the wall forming polymer of the outer layer comprises a delayed-release polymer comprising HPMCAS.
2 more elements
Dependencies are inferred from the claim text.