Rapidly infusing compositions with methotrexate and treatment methods

Abstract

A rapidly infusing composition that includes a pharmaceutically acceptable binder and/or excipient system containing gelatin and a sugar alcohol, and methotrexate. Also provided is a method of treating an autoimmune disease and/or inflammatory condition in a subject, whereby the subject in need thereof is administered, via the oral mucosa, the rapidly infusing composition. The autoimmune disease and/or inflammatory condition may include, inter alia, rheumatoid arthritis, dermatomyositis, psoriasis, systemic lupus erythematosus, eczema, vasculitis, psoriatic arthritis, type-Ii diabetes, multiple sclerosis, Crohn's disease, ulcerative colitis, and sarcoidosis, including refractory/diseases/conditions thereof.

Dependencies are inferred from the claim text.