Formulation to deter abuse of drugs by smoking
AssigneePurdue Research Foundation
InventorsLuis Solorio, Anastasiia Vasiukhina, Yoon Yeo, Sheryhan F. Gad
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Abstract
A formulation to deter abuse of a drug by smoking comprising a physical barrier having properties to entrap the drug and thermal degradation products thereof. The physical barrier is in the form of an additive or a polymer network or a combination thereof.
Claims16
A formulation to deter abuse of a drug by smoking comprising a physical barrier, wherein the physical barrier is an additive or a polymer network or a combination thereof which entraps the drug and its thermal degradation products.
A formulation to combine with a drug to deter abuse of the drug by smoking, which formulation comprises microspheres, which comprise polylactic acid and polycaprolactone in a ratio ranging from about 1:9 to about 9:1, wherein the microspheres have an average diameter from about 1.5 μm to 4.0 μm.
A method of deterring abuse of an oral dosage form of a drug, which can be abused by smoking, which method comprises incorporating into the oral dosage form of the drug a formulation comprising microspheres, which comprise polylactic acid and polycaprolactone, which entrap the drug and thermal degradation products thereof, whereupon the oral dosage form of the drug deters abuse.
Dependencies are inferred from the claim text.