# US 2023/0410307 A1 · Method and system for visualization

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- Number: US 2023/0410307 A1
- Document ID: US20230410307A1
- Status: Published application
- Kind: A1
- Application number: 18/037,586
- Filed: 2021-11-22
- Published: 2023-12-21
- Earliest claimed: 2020-11-30
- Assignees: Koninklijke Philips N.V.
- Applicants: Koninklijke Philips N.V.
- Inventors: HANNES NICKISCH; HOLGER SCHMITT; CLAAS BONTUS; RAFAEL WIEMKER
- Web page: https://patentgrep.com/patent/US20230410307A1

## CPC

- G06T 7/0014: {using an image reference approach}
- A61B 6/503: {for diagnosis of the heart}
- A61B 6/507: {for determination of haemodynamic parameters, e.g. perfusion CT}
- G06T 7/11: Region-based segmentation
- G06T 7/60: Analysis of geometric attributes
- G16H 30/40: for processing medical images, e.g. editing
- G16H 50/20: for computer-aided diagnosis, e.g. based on medical expert systems
- G16H 50/30: for calculating health indices; for individual health risk assessment
- G16H 50/50: for simulation or modelling of medical disorders
- G06T 2207/10081: Computed x-ray tomography [CT]
- G06T 2207/20021: Dividing image into blocks, subimages or windows
- G06T 2207/30048: Heart; Cardiac
- G06T 2207/30104: Vascular flow; Blood flow; Perfusion
- G06T: IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- G16H: HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA

## Abstract

A method for visualization may include: obtaining data of a first perfusion measure of myocardial tissues of a patient; obtaining data of a geometry of a coronary artery of the patient; obtaining data of a second perfusion measure of the coronary artery; obtaining data of a flow impediment measure along the coronary artery based on the data of the second perfusion measure of the coronary artery; and visualizing, on a single image, the first perfusion measure of the myocardial tissues and the coronary artery, the coronary artery being overlaid with the first perfusion measure on the single image, the visualized coronary artery representing the geometry of the coronary artery and the flow impediment measure along the coronary artery.

## Claims

### Claim 1

A computer-implemented method for visualization, comprising:
obtaining data of a first perfusion measure of myocardial tissues of a patient;
obtaining data of a geometry of a coronary artery of the patient;
obtaining data of a second perfusion measure of the coronary artery;
obtaining data of a flow impediment measure along the coronary artery based on the data of the second perfusion measure of the coronary artery; and
visualizing, on a single image, the first perfusion measure of the myocardial tissues and the coronary artery, the coronary artery being overlaid with the first perfusion measure on the single image, the visualized coronary artery representing the geometry of the coronary artery and the flow impediment measure along the coronary artery.

### Claim 2 (depends on 1)

The method of claim 1, wherein the obtaining of the data of the flow impediment measure along the coronary artery includes:
determining a flow deviation of the second perfusion measure from a reference value along the coronary artery; and
processing a stenosis assessment along the coronary artery based on the determined flow deviation to obtain the data of the flow impediment measure.

### Claim 3 (depends on 2)

The method of claim 2, wherein the processing of the stenosis assessment along the coronary artery includes:
determining a plurality of stenosis rates along the coronary artery based on the flow deviation; and
processing a cumulative sum of the stenosis rates to obtain the data of the flow impediment measure.

### Claim 4 (depends on 1)

The method of claim 1, wherein the visualizing includes simultaneously visualizing on the single image the first perfusion measure of the myocardial tissues and the coronary artery that represents the geometry of the coronary artery and that represents the flow impediment measure along the coronary artery.

### Claim 5 (depends on 1)

The method of claim 1, wherein the visualizing includes visualizing the first perfusion measure and the flow impediment measure by at least one of color, thickness, and size.

### Claim 6 (depends on 1)

The method of claim 1, further comprising obtaining coronary computed tomography angiography data of the patient,
wherein the obtaining of the data of the first perfusion measure, the obtaining of the data of the geometry of the coronary artery, and the obtaining of the data of the flow impediment measure along the coronary artery are based on the same coronary computed tomography angiography data.

### Claim 7 (depends on 1)

The method of claim 1, further comprising:
segmenting image data of the patient in accordance with a segment model of a myocardium wall to provide segmented data of the myocardium wall, wherein the obtaining of the data of the first perfusion measure of the myocardial tissues is based on the segmented data of the myocardium wall;
segmenting the image data of the patient in accordance with a segment model of the coronary artery to provide segmented data of the coronary artery, wherein the obtaining of the data of the geometry of the coronary artery of the patient and the obtaining of the data the flow impediment measure along the coronary artery are based on the segmented data of the coronary artery;
reformatting the data of the first perfusion measure of the myocardial tissues, the data of the geometry of the coronary artery, and the data of the flow impediment measure along the coronary artery, to fit a reference shape, wherein the reference shape is defined by at least an inner reference surface and an outer reference surface.

### Claim 8 (depends on 7)

The method of claim 7, further comprising:
mapping, to a target shape, the reformatted data of the myocardial tissues, the reformatted data of the geometry of the coronary artery, and the reformatted data of the flow impediment measure along the coronary artery, wherein the target shape is defined by at least a first target surface and a second target surface, wherein the mapping includes mapping from the inner reference surface to the first target surface and from the outer reference surface to the second target surface; and
based on the mapping, visualizing, on the single image, the first perfusion measure of the myocardial tissues and the coronary artery that represents the geometry of the coronary artery and that represents the flow impediment measure along the coronary artery.

### Claim 9

A visualization system, comprising:
a memory that stores a plurality of instructions; and
processor circuitry that couples to the memory and is configured to execute the instructions to:
obtain data of a first perfusion measure of myocardial tissues of a patient;
obtain data of a geometry of a coronary artery of the patient;
obtain data of a second perfusion measure of the coronary artery;
obtain data of a flow impediment measure along the coronary artery based on the data of the second perfusion measure of the coronary artery; and
visualize, on a single image, the first perfusion measure of the myocardial tissues and the coronary artery, the coronary artery being overlaid with the first perfusion measure on the single image, the visualized coronary artery representing the geometry of the coronary artery and the flow impediment measure along the coronary artery.

### Claim 10 (depends on 9)

The visualization system of claim 9, wherein the processor circuitry is further configured to:
determine a flow deviation of the second perfusion measure from a reference value along the coronary artery; and
process a stenosis assessment along the coronary artery based on the determined flow deviation to obtain the data of the flow impediment measure.

### Claim 11 (depends on 10)

The visualization system of claim 10, wherein the processor circuitry is further configured to:
determine a plurality of stenosis rates along the coronary artery based on the flow deviation; and
process a cumulative sum of the stenosis rates to obtain the data of the flow impediment measure.

### Claim 12 (depends on 9)

The visualization system of claim 9, wherein the visualizing includes simultaneously visualizing on the single image the first perfusion measure of the myocardial tissues and the coronary artery that represents the geometry of the coronary artery and that represents the flow impediment measure along the coronary artery.

### Claim 13 (depends on 9)

The visualization system of claim 9, wherein the visualizing includes visualizing the first perfusion measure and the flow impediment measure by at least one of color, thickness, and size.

### Claim 14 (depends on 9)

The visualization system of claim 9, further comprising an imaging device that is configured to obtain coronary computed tomography angiography data of the patient,
wherein the processor circuitry is configured to obtain the data of the first perfusion measure, the data of the geometry of the coronary artery, and the data of the flow impediment measure along the coronary artery, based on the same coronary computed tomography angiography data.

### Claim 15

A non-transitory computer-readable medium having one or more executable instructions stored thereon, which, when executed by processor circuitry, cause the processor circuitry to perform a method for visualization, comprising:
obtaining data of a first perfusion measure of myocardial tissues of a patient;
obtaining data of a geometry of a coronary artery of the patient;
obtaining data of a second perfusion measure of the coronary artery;
obtaining data of a flow impediment measure along the coronary artery based on the data of the second perfusion measure of the coronary artery; and
visualizing, on a single image, the first perfusion measure of the myocardial tissues and the coronary artery, the coronary artery being overlaid with the first perfusion measure on the single image, the visualized coronary artery representing the geometry of the coronary artery and the flow impediment measure along the coronary artery.