Targeting host-bacteria interactions for the treatment of microbiota-mediated diseases
OwnerConnor Rosen, Noah Palm +1inventors
InventorsConnor Rosen, Noah Palm, Aaron Ring
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Abstract
The present invention generally relates to compositions and methods for modulating specific paired host protein-microbiota interactions and the use thereof for the prevention and treatment of diseases and disorders.
Claims20
A composition for modulating an interaction of a host protein with an associated microbial cell, wherein the host protein and microbial cell are interacting partners selected from the group consisting of host protein and microbial cell interacting partners as set forth in Table 1.
A method of modulating an interaction of a host protein with an associated microbial cell, wherein the host protein and microbial cell are interacting partners selected from the group consisting of host protein and microbial cell interacting partners as set forth in Table 1, the method comprising contacting a host cell with a composition for modulating the interaction of the host protein and the microbial cell.
A method of treating or preventing a disease or disorder in a subject in need thereof, the method comprising administering a composition for modulating the interaction of a host protein and a microbial cell to the subject, wherein the host protein and microbial cell are interacting partners selected from the group consisting of host protein and microbial cell interacting partners as set forth in Table 1.
Dependencies are inferred from the claim text.