Microorganisms and methods for the continuous production of ethylene from c1-substrates
AssigneeLanzaTech, Inc.
InventorsSean Dennis Simpson, Jennifer Rosa Holmgren, James MacAllister Clomburg, Jim Jeffrey Daleiden, Audrey Jean Harris, Stephanie Rhianon Jones, Michael Koepke, Timothy James Politano
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Abstract
Methods and microorganisms are genetically engineered to continuously produce ethylene by microbial fermentation, particularly by the microbial fermentation of a gaseous substrate. The microorganisms are C1-fixing. Further, the gaseous substrate comprises CO2 and an energy source. The production of ethylene can be improved by varying promoters or nutrient limiting means.
Claims20
A recombinant C1-fixing microorganism capable of producing ethylene from a gaseous substrate comprising a nucleic acid encoding a group of exogenous enzymes comprising ethylene-forming enzyme (EFE).
A recombinant C1-fixing microorganism capable of switching cellular burden in production of ethylene, the microorganism comprising a nucleic acid encoding a group of exogenous enzymes comprising ethylene-forming enzyme (EFE) and one or more inducible promoters.
Dependencies are inferred from the claim text.