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US 2023/0406936 A1Published application
Anti-pd-l1 antibody and use thereof
AssigneeImmunourchin
InventorJun ZHOU
Life of this patent
Estimating the term…
Abstract
A PD-L1 antibody or an active fragment thereof does not block the binding of PD-1 with PD-L1, and specifically targets the IgC-like region of PD-L1. The non-blocking PD-L1 antibody can circumvent SPD-L1 to the maximum extent, and has the activity of inducing ADCC/CDC functional effects whilst also having excellent anti-tumor activity.
Claims18
A PD-L1 antibody or an active fragment thereof, wherein the antibody does not block the binding of PD-L1 with PD-1 and specifically binds to pan IgC segment of PD-L1 and has ADCC/CDC functional effects activity.
Dependencies are inferred from the claim text.