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US 2023/0405528 A1Published application
Perfusion filtration system
AssigneeWaterSep BioSeparations LLC
InventorsAttila Herczeg, Julie-Anne Burdick
Life of this patent
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Abstract
Disclosed herein is a perfusion filtration module or bioreactor for filtering a fluid, wherein the filtration module or bioreactor has a plurality of hollow fiber filter membranes that are splayed to reduce fouling of the filtration array.
Claims17
A perfusion filtration module for filtering a feed fluid, comprising:
- a. a plurality of hollow fiber filter membranes, each having a first end and a second end, wherein the first ends of the hollow fiber filter membranes are potted, thus forming a first potted end, to enable filtrate flow from the hollow fiber filter membranes, and wherein the second ends of the hollow fiber filter membranes are either:
- i. potted, thus forming a second potted end, to enable fluid flow from the hollow fiber filter membranes;
- or alternatively
- ii. mounted, thus forming a mounted end, so that the hollow fiber filter membranes are sealed to prevent filtrate flow;
- and
- b. a constraint that allows the hollow fiber filter membranes to be held in a splayed configuration, wherein:
- i. the first potted end and the second potted end;
- or alternatively
- ii. the first potted end and the mounted end,
- comprise first and second surfaces, respectively, from which the fiber filter membranes emerge,
- wherein the splayed configuration is a configuration in which the hollow fiber filter membranes spread out from one another as they extend away from the first potted end and the second potted end, or the mounted end, to increase an interstitial distance between adjacent ones of the plurality of hollow fiber filter membranes across a width of the perfusion filtration module between the first potted end and the second potted end, or the mounted end.
8 more elements
A membrane bioreactor comprising:
- a perfusion filtration module for filtering a feed fluid, said perfusion filtration module comprising:
- a. a plurality of hollow fiber filter membranes, each having a first end and a second end, wherein the first ends of the hollow fiber filter membranes are potted, thus forming a first potted end, to enable filtrate flow from the hollow fiber filter membranes, and wherein the second ends of the hollow fiber filter membranes are either:
- i. potted, thus forming a second potted end, to enable fluid flow from the hollow fiber filter membranes;
- or alternatively
- ii. mounted, thus forming a mounted end, so that the hollow fiber filter membranes are sealed to prevent filtrate flow;
- and
- b. a constraint that allows the hollow fiber filter membranes to be held in a splayed configuration, wherein:
- i. the first potted end and the second potted end;
- or alternatively
- ii. the first potted end and the mounted end,
- comprise first and second surfaces, respectively, from which the fiber filter membranes emerge,
- wherein the splayed configuration is a configuration in which the hollow fiber filter membranes spread out from one another as they extend away from the first potted end and the second potted end, or the mounted end, to increase an interstitial distance between adjacent ones of the plurality of hollow fiber filter membranes across a width of the perfusion filtration module between the first potted end and the second potted end, or the mounted end.
9 more elements
Dependencies are inferred from the claim text.