Method of treating breast cancer
AssigneeEisai R&D Management Co., Ltd.
InventorAntonio GUALBERTO
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Abstract
The present invention relates to methods of treating breast cancer patients with Compound 1 or pharmaceutically acceptable salts thereof. In some embodiments, the invention relates to treating patients meeting mutant allele frequency threshold values.
Claims29
A method of treating breast cancer comprising administering Compound 1 or a pharmaceutically acceptable salt thereof to a patient having a first mutant allele frequency (“MAF”) value of a first ERα mutant greater than or equal to 0.5%.
The method according to any one of the claims above, wherein said patient has PgR positive status.
A method of treating a cancer in a patient, comprising administering Compound 1 or a pharmaceutically acceptable salt thereof to a patient having a first mutant allele frequency (“MAF”) value of a first ERα mutant greater than or equal to 0.5%.
The method of any preceding claim, wherein MAF is measured in a blood sample from a patient.
The method of any preceding claim, wherein MAF is measured in cfDNA from a blood sample from a patient.
Dependencies are inferred from the claim text.