Compositions to limit or eliminate the perception of sweat malodor
AssigneeFirmenich SA
InventorsChristine VUILLEUMIER, Gary MARR, Jessica BRANN, Lily WU, Zhenan WU, Nicholas O'LEARY, Benjamin SMITH
Life of this patent
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Abstract
The various aspects presented herein relate to the perfumery industry. More particularly, the various aspects presented herein relate to the use of volatile compositions to limit, decrease or eliminate the perception of sweat malodor. Such compositions include at least one malodor antagonist optionally combined with perfuming ingredients. Such compositions, their use in combination with delivery systems and their applications in consumer products are also objects of the present disclosure.
Claims20
A method to inhibit, reduce, or suppress the perception of a sweat malodor in a subject, which comprises contacting the subject with a composition comprising a compound selected from the group consisting of:
- (+−)-2,6-dimethyl-2-octanol;
- allyl heptanoate;
- (2E)-3-phenyl-2-prop en-1-ol;
- (+−)-2,2,5-trimethyl-5-pentylcyclopentanone;
- (+−)-3,7-dim ethyl-3-octanol;
- methyl 2-octynoate;
- (+−)-2-methylundecanal;
- (+−)-methyl 2,2-dimethyl-6-methylidenecyclohexanecarboxylate;
- ethyl (E)-3-phenyl-2-propenoate;
- methyl (E)-3-phenyl-2-propenoate;
- 1-(2-naphthyl)ethenone;
- (10E)-oxacycloheptadec-10-en-2-one;
- 4-(4-hydroxyphenyl)-2-butanone;
- (+−)-6-m ethoxy-2,6-dimethylheptanal;
- ethyltricyclo[5.2.1.0.(2,6)] decane-2-carboxylate;
- 4-methoxybenzyl acetate;
- (3Z)-3-hexen-1-ol;
- pentyl 2-hydroxybenzoate;
- allyl hexanoate;
- tricyclo[5.2.1.0(2,6)] dec-3-en-8-yl propanoate;
- (2RS,4SR)-4-methyl-2-phenyltetrahydro-2H-pyran;
- (+−)-3-(4-m ethoxyphenyl)-2-m ethylprop anal;
- (+−)-3-(1,3-benzodioxol-5-yl)-2-m ethylprop anal;
- 2,6-dim ethyl-4-heptanol;
- benzophenone;
- (2Z)-1,1-dimethoxy-3,7-dimethyl-2,6-octadiene;
- 4-isopropylbenzaldehyde;
- (+−)-4-nonanolide;
- (E)-4-decenal;
- (Z)-3,7-dimethyl-1,3,6-octatriene;
- 3-phenylpropanal;
- 2-methoxynaphthalene;
- 2-ethyl-3-hydroxy-4(4H)-pyranone;
- (+−)-2-(4-methyl-3-cyclohexen-1-yl)-2-propanyl acetate;
- (E)-3,7-dim ethyl-2,6-octadien-1-ol;
- ethyl 2-methyl-1,3-di oxolane-2-acetate;
- 3-(4-ethylphenyl)-2,2-dimethylpropanal;
- (2RS,4 SR)-4-methyl-2-(2-methyl-1-prop en-1-yl)tetrahydro-2H-pyran;
- (3 aRS, 5 aSR,9aSR,9bRS)-3a,6,6,9a-tetramethyl dodecahydronaphtho[2,1-b] furan;
- (2,2-dimethoxyethyl)benzene;
- (+−)-(5E)-3-methyl-4-methoxybenzaldehyde;
- 10-undecenal;
- (2E)-2-nonenal;
- 4-phenyl-2-butanone;
- (+−)-(6E)-3,7-dim ethyl-1,6-nonadien-3-yl acetate;
- ethyl 1RS,2 SR, 3 SR,4 SR-3-isopropylbicyclo[2.2.1] hept-5-ene-2-carboxylate;
- 3-ethoxy-4-hydroxybenzaldehyde;
- methyl 2-((1RS,2RS)-3-oxo-2-pentylcyclopentyl)acetate;
- (+−)-2,6-dimethyl-7-octen-2-ol;
- (+−)-6-sec-butyl quinoline;
- (+−)-3,7-dimethyl-6-octenal;
- methyl 2,4-dihydroxy-3,6-dimethylbenzoate;
- 4-cyclohexyl-2-methyl-2-butanol;
- (3E)-4-(2,6,6-trimethyl-1-cyclohexen-1-yl)-3-buten-2-one;
- (−)-(2E)-2-ethyl-4-[(1R)-2,2,3-tri methyl-3-cyclopenten-1-yl]-2-buten-1-ol;
- 1-(3, 3/5, 5-di methyl-1-cyclohexen-1-yl)-4-penten-1-one;
- (+)-(3R,5Z)-3-methyl-5-cyclopentadecen-1-one;
- patchouli oil;
- thymol;
- (+−)-(3E)-4-(2,6,6-trimethyl-1/2-cyclohexen-1-yl)-3-buten-2-one;
- 2-(3-phenyl propyl)pyri dine;
- (+−)-(2E)-1-(2,6,6-tri methyl-2-cyclohexen-1-yl)-2-buten-1-one;
- (+−)-3, 5,6,6-tetramethyl-4-methylidene-2-heptanone;
- (4E)-3,4, 5,6,6-pentamethyl-4-hepten-2-one;
- 3,4, 5,6,6-pentamethyl-3-hepten-2-one;
- (2E,6Z)-2,6-nonadienal;
- (+−)-(E)-4-methyl-3-dec en-5-ol;
- 2-chromenone;
- (+−)-(3E)-3-methyl-4-(2,6,6-trimethyl-2-cyclohexen-1-yl)-3-buten-2-one;
- (+−)-(1E)-1-(2,6,6-tri methyl-2-cyclohexen-1-yl)-1-penten-3-one;
- (+−)-(2,5-di methyl-2,3-dihydro-1H-inden-2-yl)methanol;
- (E)-2-ethoxy-5-(1-propenyl)phenol;
- undecanal;
- 1-[(1RS,2RS)-1,2, 8,8-tetramethyl-1,2,3,4, 5, 6,7,8-octahydro-2-naphthalenyl] ethenone;
- 1-((2RS,3RS)-2,3, 8,8-tetramethyl-1,2,3,4, 5, 6,7,8-octahydronaphthalen-2-yl)ethenone;
- 1-[(2RS, 3 RS, 8 aRS)-2,3, 8,8-tetramethyl-1,2,3, 5,6,7,8,8a-octahydro-2-naphthalenyl] ethenone;
- 1-[(1RS,2RS, 8aSR)-1,2, 8,8-tetramethyl-1,2,3, 5,6,7,8,8a-octahydro-2-naphthalenyl] ethenone;
- 1-[(2RS, 3 RS, 8 aRS)-2,3, 8,8-tetramethyl-1,2,3,4,6, 7, 8,8a-octahydro-2-naphthalenyl] ethenone;
- 2-phenylethanol, (4Z)-4-dodecenal;
- octanal;
- decanal;
- (+−)-tetrahydro-2-isobutyl-4-methyl-4(2H)-pyranol;
- (1RS,2RS)-2,4-dimethyl-3-cyclohexene-1-carb aldehyde, (1RS,2SR)-2,4-dimethyl-3-cyclohexene-1-carbaldehyde;
- and combinations thereof;
- wherein the subject's perception of the sweat malodor is inhibited, reduced or suppressed.
A sweat malodor inhibiting composition comprising a compound selected from the group consisting of:
- (+−)-2,6-dim ethyl-2-octanol allyl heptanoate;
- (2E)-3-phenyl-2-prop en-1-ol (+−)-2,2,5-trimethyl-5-pentylcyclopentanone;
- (+−)-3,7-dim ethyl-3-octanol;
- methyl 2-octynoate;
- (+−)-2-methylundecanal;
- (+−)-methyl 2,2-dimethyl-6-methylidenecyclohexanecarboxylate;
- ethyl (E)-3-phenyl-2-propenoate;
- methyl (E)-3-phenyl-2-propenoate;
- 1-(2-naphthyl)ethenone;
- (10E)-oxacycloheptadec-10-en-2-one;
- 4-(4-hydroxyphenyl)-2-butanone;
- (+−)-6-methoxy-2,6-dimethylheptanal;
- ethyltricyclo [5.2.1.0.(2,6)]decane-2-carboxylate;
- 4-methoxybenzyl acetate;
- (3Z)-3-hexen-1-ol;
- pentyl 2-hydroxybenzoate;
- allyl hexanoate;
- tricyclo[5.2.1.0(2,6)]dec-3-en-8-yl propanoate;
- (2RS,4SR)-4-methyl-2-phenyltetrahydro-2H-pyran;
- (+−)-3-(4-m ethoxyphenyl)-2-methyl prop anal;
- (+−)-3-(1,3-benzodioxol-5-yl)-2-methyl prop anal;
- 2,6-dim ethyl-4-heptanol benzophenone;
- (2Z)-1,1-dimethoxy-3,7-dimethyl-2,6-octadiene;
- 4-isopropylbenzaldehyde;
- (+−)-4-nonanolide;
- (E)-4-decenal;
- (Z)-3,7-dimethyl-1,3,6-octatriene;
- 3-phenylpropanal;
- 2-methoxynaphthalene;
- 2-ethyl-3-hydroxy-4(4H)-pyranone;
- (+−)-2-(4-methyl-3-cyclohexen-1-yl)-2-propanyl acetate;
- (E)-3,7-dim ethyl-2,6-octadien-1-ol;
- ethyl 2-methyl-1,3-dioxolane-2-acetate;
- 3-(4-ethylphenyl)-2,2-dimethylpropanal;
- (2RS,4 SR)-4-methyl-2-(2-methyl-1-prop en-1-yl)tetrahydro-2H-pyran;
- (3 aRS, 5 aSR,9aSR,9bRS)-3a,6,6,9a-tetramethyl dodecahydronaphtho[2,1-b]furan;
- (2,2-dimethoxyethyl)benzene;
- (+−)-(5E)-3-methyl-5-cyclopentadecen-1-one;
- 4-methoxybenzaldehyde;
- 10-undecenal;
- (2E)-2-nonenal;
- 4-phenyl-2-butanone;
- (+−)-(6E)-3,7-dimethyl-1,6-nonadien-3-yl acetate;
- ethyl 1RS,2SR,3 SR,4 SR-3-isopropylbicyclo[2.2.1]hept-5-ene-2-carboxylate;
- 3-ethoxy-4-hydroxybenzaldehyde;
- methyl 2-((1RS,2RS)-3-oxo-2-pentylcyclopentyl)acetate;
- (+−)-2,6-dimethyl-7-octen-2-ol;
- (+−)-6-sec-butyl quinoline;
- (+−)-3,7-dimethyl-6-octenal;
- methyl 2,4-dihydroxy-3,6-dimethylbenzoate;
- 4-cyclohexyl-2-methyl-2-butanol (3E)-4-(2,6,6-trimethyl-1-cyclohexen-1-yl)-3-buten-2-one;
- (−)-(2E)-2-ethyl-4-[(1R)-2,2,3-trimethyl-3-cyclopenten-1-yl]-2-buten-1-ol;
- 1-(3,3/5, 5-dimethyl-1-cyclohexen-1-yl)-4-penten-1-one;
- (+)-(3R,5Z)-3-methyl-5-cyclopentadecen-1-one;
- patchouli oil;
- thymol;
- (+−)-(3E)-4-(2,6,6-trimethyl-1/2-cyclohexen-1-yl)-3-buten-2-one;
- 2-(3-phenylpropyl)pyri dine;
- (+−)-(2E)-1-(2,6,6-trimethyl-2-cyclohexen-1-yl)-2-buten-1-one;
- (+−)-3, 5,6,6-tetramethyl-4-methylidene-2-heptanone;
- (4E)-3,4,5,6,6-pentamethyl-4-hepten-2-one;
- 3,4, 5,6,6-pentamethyl-3-hepten-2-one;
- (2E,6Z)-2, 6-nonadienal (+−)-(E)-4-methyl-3-dec en-5-ol 2-chromenone;
- (+−)-(3E)-3-methyl-4-(2, 6,6-trimethyl-2-cyclohexen-1-yl)-3-buten-2-one;
- (+−)-(1E)-1-(2,6, 6-trimethyl-2-cyclohexen-1-yl)-1-penten-3-one;
- (+−)-(2, 5-dim ethyl-2,3-dihydro-1H-inden-2-yl)methanol (E)-2-ethoxy-5-(1-propenyl)phenol;
- undecanal;
- 1-[(1RS,2RS)-1,2, 8, 8-tetramethyl-1,2,3,4,5, 6,7, 8-octahydro-2-naphthalenyl] ethenone;
- 1-((2RS,3RS)-2,3, 8, 8-tetramethyl-1,2,3,4,5, 6,7, 8-octahydronaphthalen-2-yl)ethenone;
- 1-[(2RS,3RS, 8 aRS)-2,3, 8, 8-tetramethyl-1,2,3,5,6,7, 8, 8a-octahydro-2-naphthalenyl] ethenone;
- 1-[(1RS,2RS, 8aSR)-1,2, 8, 8-tetramethyl-1,2,3,5,6,7, 8, 8a-octahydro-2-naphthalenyl] ethenone;
- 1-[(2RS,3RS, 8 aRS)-2,3, 8, 8-tetramethyl-1,2,3,4,6,7, 8, 8a-octahydro-2-naphthalenyl] ethenone;
- 2-phenylethanol, (4Z)-4-dodecenal;
- octanal;
- decanal;
- (+−)-tetrahydro-2-isobutyl-4-methyl-4(2H)-pyranol;
- (1RS,2RS)-2,4-dimethyl-3-cyclohexene-1-carb aldehyde, (1RS,2SR)-2,4-dimethyl-3-cyclohexene-1-carbaldehyde;
- and combinations thereof;
- and a perfume ingredient or an excipient selected from the group consisting of:
- a humectant, an emollient an antioxidant, a pH adjustor, a coloring agent, a preservative, a thickening agent, a stabilizer, a propellant, a solvent, a cooling agent, and combinations thereof.
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An antiperspirant or deodorant composition comprising:
- a) at least one ingredient selected from the group consisting of (3E)-4-(2,6,6-trimethyl-1-cyclohexen-1-yl)-3-buten-2-one, (+−)-2-methylundecanal, (−)-(2E)-2-ethyl-4-[(1R)-2,2,3-trimethyl-3-cyclopenten-1-yl]-2-buten-1-ol, 1-(3,3/5,5-dim ethyl-1-cyclohexen-1-yl)-4-penten-1-one, methyl 2,4-dihydroxy-3,6-dimethylbenzoate, (+)-(3R,5Z)-3-methyl-5-cyclopentadecen-1-one, patchouli oil, thymol, (+−)-(3E)-4-(2,6, 6-trimethyl-1/2-cyclohexen-1-yl)-3-buten-2-one, 2-(3-phenylpropyl)pyri dine, (+−)-(2E)-1-(2, 6,6-trimethyl-2-cyclohexen-1-yl)-2-buten-1-one, (+−)-6/8-sec-butyl quinoline, (+−)-3,5, 6,6-tetramethyl-4-methylidene-2-heptanone, (4E)-3,4, 5,6, 6-pentamethyl-4-hepten-2-one, 3,4,5,6,6-pentamethyl-3-hepten-2-one, 1-(2-naphthyl)ethanone, methyl 2-((1RS,2RS)-3-oxo-2-pentylcyclopentyl)acetate, (2E,6Z)-2,6-nonadienal, (+−)-(E)-4-methyl-3-decen-5-ol and combinations thereof;
- b) at least two ingredients and selected from the group consisting of (3 aRS, 5aSR,9aSR,9bRS)-3a,6,6,9a-tetramethyldodecahydronaphtho[2, 1-b]furan, 4-methoxybenzaldehyde, 4-(4-hydroxyphenyl)-2-butanone, tricyclo[5.2.1.0(2,6)]dec-3/4-en-8-yl propanoate, 2-chromenone, (+−)-(3E)-3-methyl-4-(2,6,6-trimethyl-2-cyclohexen-1-yl)-3-buten-2-one, (+−)-(1E)-1-(2,6,6-trimethyl-2-cyclohexen-1-yl)-1-penten-3-one, (+−)-(2, 5-dimethyl-2,3-dihydro-1H-inden-2-yl)methanol, (E)-2-ethoxy-5-(1-prop enyl)phenol, undecanal, 1-[(1RS,2RS)-1,2,8, 8-tetramethyl-1,2,3,4, 5,6,7, 8-octahydro-2-naphthalenyl] ethenone, 1-((2RS,3RS)-2,3, 8, 8-tetramethyl-1,2,3,4, 5,6,7, 8-octahydronaphthalen-2-yl)ethanone, 1-[(2RS, 3RS, 8 aRS)-2,3, 8, 8-tetramethyl-1,2,3,5,6,7,8,8a-octahydro-2-naphthalenyl]ethenone, 1-[(1RS,2RS,8aSR)-1,2, 8,8-tetramethyl-1,2,3,5,6,7,8,8a-octahydro-2-naphthalenyl]ethenone, 1-[(2RS,3RS,8aRS)-2,3,8, 8-tetramethyl-1,2,3,4, 6,7, 8,8a-octahydro-2-naphthalenyl] ethanone, (+−)-2,6-dimethyl-7-octen-2-ol, 2-phenylethanol, (3Z)-3-hexen-1-ol, (4Z)-4-dodecenal, octanal, decanal, 10-undecenal, 3-ethoxy-4-hydroxybenzaldehyde, 2-ethyl-3-hydroxy-4(4H)-pyranone, (E)-3,7-dim ethyl-2,6-octadien-1-ol, (+−)-tetrahydro-2-isobutyl-4-methyl-4(2H)-pyranol, (1RS,2RS)-2,4-dimethyl-3-cyclohexene-1-carb aldehyde, (1RS,2SR)-2,4-dimethyl-3-cyclohexene-1-carbaldehyde, (+−)-3/4-(4-methyl-3-penten-1-yl)-3-cyclohexene-1-carbaldehyde and combinations thereof.
Dependencies are inferred from the claim text.