Systems and methods for navigational bronchoscopy and selective drug delivery
AssigneeCovidien LP
InventorWilliam S. Krimsky
Life of this patent
Estimating the term…
Abstract
Provided in accordance with the present disclosure is a diagnostic and a therapeutic bronchoscopy system for localized delivery of medication within the lungs. Specifically, systems and methods are disclosed for creating a functional and anatomical map of the lungs, diagnosing a condition within the lungs, generating a treatment plan for a target site within the lungs, navigating to the target site, administering a treatment directly to the target site for immediate absorption within the target site, and assessing the efficacy of the treatment.
Claims22
1-20. (canceled)
A system, comprising:
- a display device configured to display a user interface, the user interface including a 3D model of a luminal network for navigating to a target site within the luminal network;
- and
- a medical tool navigable through the luminal network to the target site, the medical tool including:
- a flexible elongate member;
- and
- an agent dispenser operably coupled to the flexible elongate member, the agent dispenser defining:
- a reservoir configured to store at least one of a therapeutic or diagnostic agent;
- a lumen in fluid communication with the reservoir;
- and
- a nozzle operably coupled to the lumen, wherein the agent dispenser is configured to dispense aerosolized particles to the target site from the reservoir through the lumen, and from the lumen through the nozzle, the flexible elongate member and the agent dispenser configured for advancement through the luminal network to deliver the aerosolized particles to the target site for absorption within the target site.
A medical tool, comprising:
- a flexible elongate member configured to navigate through a luminal network to a target site via a guide catheter;
- and
- a diagnostic agent dispenser operably coupled to the flexible elongate member, the diagnostic agent dispenser including:
- a reservoir configured to store a diagnostic agent, the diagnostic agent selected from the group consisting of inorganic and organic compounds, dyes, stains, radioactive tracers, and culture-media chemical based constituents;
- a lumen in fluid communication with the reservoir;
- and
- a nozzle operably coupled to the lumen, wherein the diagnostic agent dispenser is configured to dispense aerosolized particles of the diagnostic agent from the reservoir through the lumen and out of the nozzle for diagnosing the target site.
A medical tool, comprising:
- a flexible elongate member configured to navigate through a luminal network to a target site via a guide catheter;
- and
- a therapeutic agent dispenser removably coupled to the flexible elongate member, the therapeutic agent dispenser including:
- a reservoir configured to store a therapeutic agent therein, the therapeutic agent selected from the group consisting of bronchodilators, corticosteroids, methylxanthines, beta-agonists, inhibitors, antimicrobials, antitumor agents, antifibrotic agents, biologic agents, immunotherapy, gene vectors, radio-labeled and auto fluorescing ligands;
- a lumen in fluid communication with the reservoir;
- and
- a nozzle operably coupled to the lumen, wherein the therapeutic agent dispenser is configured to dispense aerosolized particles of the therapeutic agent from the reservoir through the lumen to treat the target site.
(canceled)
Dependencies are inferred from the claim text.