Systems and methods for compensating for agent elution

A glucose monitoring system comprising:

• a glucose sensor including a first flex having a working electrode and a second flex being covered with an agent, which lengthens a lifetime of the glucose sensor, and monitoring a level of glucose in a body of a user;
• and
• a controller configured to:
• access a first electrochemical impedance spectroscopy (EIS) value of at least one parameter, the first EIS value based on first EIS signals from the working electrode at an initiation time when the first flex and the second flex enter into the body of the user and the glucose sensor initiates sensing a level of glucose;
• access a second EIS value of the at least one parameter, the second EIS value based on second EIS signals from the working electrode at a second time after the initiation time;
• calculate a change in the at least one parameter between the first EIS value and the second EIS value;
• estimate a concentration of the agent based on the change in the at least one parameter;
• determine whether a model effect in response to the concentration is greater than a threshold;
• and
• in a case where the model effect is determined to be greater than the threshold:
• adjust a sensor glucose value based on the concentration and sensor signals from the working electrode;
• and
• display the adjusted sensor glucose value.

A non-transitory processor readable medium including instructions stored thereon which, when executed by a processor, causes performance of a method for compensating for an agent, which lengthens a lifetime of a glucose sensor monitoring a level of glucose in a body of a user, the glucose sensor including a first flex having a working electrode and a second flex being coated with the agent, the method comprising:

• accessing a first electrochemical impedance spectroscopy (EIS) value of at least one parameter, the first EIS value based on first EIS signals from the working electrode at an initiation time when the first flex and the second flex enter into the body of the user and the glucose sensor initiates sensing a level of glucose;
• accessing a second EIS value of the at least one parameter, the second EIS value based on second EIS signals from the working electrode at a second time after the initiation time;
• calculating a change in the at least one parameter between the first EIS value and the second EIS value;
• estimating a concentration of the agent based on the change in the at least one parameter;
• calculating a model effect in response to the concentration;
• determining whether the model effect is greater than a threshold;
• and
• in a case where the model effect is determined not to be greater than the threshold:
• adjusting a sensor glucose value based on the concentration and sensor signals from the working electrode;
• and
• displaying the adjusted sensor glucose value.

A glucose monitoring system comprising:

• a glucose sensor including a flex having a working electrode and monitoring a level of glucose in a body of a user, wherein a portion of the flex is covered with an agent, which lengthens a lifetime of the glucose sensor;
• and
• a controller configured to:
• access a first electrochemical impedance spectroscopy (EIS) value of at least one parameter, the first EIS value based on first EIS signals from the working electrode at an initiation time when the flex enters into the body of the user and the glucose sensor initiates sensing a level of glucose;
• access a second EIS value of the at least one parameter, the second EIS value based on second EIS signals from the working electrode at a second time after the initiation time;
• calculate a change in the at least one parameter between the first EIS value and the second EIS value;
• estimate a concentration of the agent based on the change in the at least one parameter;
• determine whether a model effect in response to the concentration is greater than a threshold;
• and
• in a case where the model effect is determined not to be greater than the threshold:
• adjust a sensor glucose value based on the concentration;
• and
• display the adjusted sensor glucose value.