Systems, devices, and methods for meal-related analyte response monitoring

A system for monitoring meal-related glucose responses in a subject, the system comprising:

• a reader device, comprising:
• wireless communication circuitry configured to receive data indicative of a glucose level of the subject,
• one or more processors coupled with a memory, the memory storing a meal monitoring application that, when executed by the one or more processors, causes the one or more processors to:
• identify a peak glucose level value within a predetermined time period for the received data indicative of the glucose level of the subject,
• determine an estimated meal start time and an initial glucose level value based on the peak glucose level value,
• determine a glucose level variance value,
• prompt the subject to enter meal information, and
• associate the entered meal information with the glucose level variance value.