Electrochemical sensor
AssigneeUniversity of Strathclyde
InventorsDamion K. Corrigan, Vincent James Vezza
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Abstract
The present disclosure relates to an electrochemical sensor, which employ fluoro organothiol or fluoro organosilane molecules in the formation of self-assembled monolayer (SAM) for use in diagnosis tests. There is also provided methods of testing a patient sample using the electrochemical sensor as disclosed.
Claims21
An electrochemical biosensor for use in detecting a target analyte, the sensor comprising:
- at least one detection electrode comprising a surface coated with a self-assembled monolayer (SAM), wherein the SAM comprises, consists essentially of, or consists of a hydrofluorocarbon or fluorocarbon molecule bound to the surface of the electrode through a reactive sulphur or silicon group present on the hydrofluorocarbon or fluorocarbon.
The electrochemical biosensor according to any preceding claim, wherein the fluorocarbon molecule is a linear fluoro alkanethiol, or fluoro alkanesilane.
The electrochemical biosensor according to any preceding claim, wherein the electrode surface is formed from a glassy carbon;
- metal oxide;
- conducting polymer;
- or noble metal including gold, ruthenium, rhodium, palladium, platinum and silver.
An electrochemical biosensor according to any preceding claim, further comprising a biological agent captured by the SAM layer coated on the surface of the electrode.
Dependencies are inferred from the claim text.