Method for screening a subject for cancer

A method for screening and treating a subject for a cancer, comprising the steps of:

• i. extracting the cell free nucleic acids from a sample obtained from the subject;
• ii. denaturating the cell free nucleic acids to obtain single stranded DNA fragments;
• iii. measuring a level of a first group of single stranded DNA fragments on a specific range having a length between 20 to 400 nucleotides;
• iv. measuring a level of a second group of single stranded DNA fragments on a specific range having a length between 20 to 400 nucleotides;
• v. calculating the ratio of the level measured at step iii) to the level at step iv) or alternatively the ratio of the level determined at step iv) to the level measured at step iii;
• vi. comparing the ratio measured at step v) with a ratio of predetermined corresponding reference values;
• vii. concluding that the subject suffers from a cancer when the ratio determined at step v) differs from the predetermined corresponding reference value;
• and
• viii. administering one or more cancer treatments to a subject identified as having a a ratio that differs from the ratio of the predetermined reference values, wherein the one or more cancer treatments are selected from the group consisting of radiotherapy, chemotherapy and immunotherapy.

A method for screening and treating a subject for a cancer, comprising the steps of:

• i. extracting cell free nucleic acids from a sample obtained from the subject;
• ii. denaturating the cell free nucleic acids to obtain single stranded DNA fragments;
• iii. measuring a level of a group of single stranded DNA fragments on a specific range having a length between 20 to 400 nucleotides;
• iv. measuring a level of one single stranded DNA fragment having a length between 20 to 400 nucleotides;
• v. calculating a ratio of the level measured at step iii) to the level measured at step iv) or a ratio of the level measured at step iv) to the level measured at step iii);
• vi. comparing the ratio determined at step v) with a ratio of predetermined corresponding reference value;
• vii. concluding that the subject suffers from a cancer when the ratio determined at step v) differs from the ratio of predetermined corresponding reference value;
• and
• viii. administering one or more cancer treatments to a subject identified as having a ratio determined at step v) that differs from the ratio of corresponding predetermined reference values, wherein the one or more cancer treatments are selected from the group consisting of radiotherapy, chemotherapy and immunotherapy.