Wars-neutralizing antibody and use thereof
AssigneeMirimgene Co., Ltd.
InventorsMirim JIN, Yun Hui CHOI
Life of this patent
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Abstract
The present disclosure relates to an antibody binding specifically to tryptophanyl-tRNA synthetase (WARS) or a fragment thereof. The antibody or the fragment thereof of the present disclosure has an excellent ability to bind specifically to WARS with no cross-reactivity with other ARSs and has an excellent ability to detect WARS and inhibit the activity thereof. Therefore, it can be effectively used for diagnosing and/or treating an infectious disease.
Claims20
1-28. (canceled)
An antibody binding specifically to tryptophanyl-tRNA synthetase (WARS), comprising a heavy chain variable domain (VH) comprising a heavy chain CDR1 of SEQ ID NO 3, a heavy chain CDR2 of SEQ ID NO 4 and a heavy chain CDR3 of SEQ ID NO 5 and a light chain variable domain (VL) comprising a light chain CDR1 of SEQ ID NO 6, a light chain CDR2 of SEQ ID NO 7 and a light chain CDR3 of SEQ ID NO 8, or an antigen binding fragment thereof.
Dependencies are inferred from the claim text.