Devices and processes for delivery of therapeutic fluids

A therapeutic agent delivery system, comprising:

• a housing having a distal end portion;
• a therapeutic agent delivery assembly carried by the housing, the therapeutic agent delivery assembly comprising:
• a chamber comprising a first passageway configured to carry a therapeutic agent;
• a needle in communication with the first passageway;
• the therapeutic agent delivery assembly being translatable relative to the housing from a stowed configuration to a deployed configuration, in the deployed configuration the needle at least partially extending distally from the distal end portion of the housing, and the therapeutic agent delivery assembly being translatable relative to the housing from the deployed configuration to a retracted configuration, in the retracted configuration the needle being disposed proximally relative to the distal end portion of the housing;
• a drive mechanism carried by the housing, the drive mechanism comprising:
• a threaded nut;
• a drive screw carried by and threadably coupled to the threaded nut, the drive screw being rotatable and translatable relative to the housing to translate the therapeutic agent delivery assembly relative to the housing;
• and
• a torsion spring, the torsion spring releasing energy to rotate and translate the drive screw relative to the housing, the drive mechanism thereby translating the therapeutic agent delivery assembly from the stowed configuration to the deployed configuration and from the deployed configuration to the retracted configuration.

A therapeutic agent delivery system, comprising:

• a housing having a distal end portion;
• a therapeutic agent delivery assembly carried by the housing, the therapeutic agent delivery assembly comprising:
• a chamber comprising a first passageway;
• a therapeutic agent carried in the first passageway;
• a needle in communication with the first passageway;
• the therapeutic agent delivery assembly being translatable relative to the housing from a stowed configuration to a deployed configuration, in the deployed configuration the needle at least partially extending distally from the distal end portion of the housing, and the therapeutic agent delivery assembly being translatable relative to the housing from the deployed configuration to a retracted configuration, in the retracted configuration the needle being disposed proximally relative to the distal end portion of the housing;
• a drive mechanism carried by the housing, the drive mechanism comprising:
• a retraction cap;
• a threaded nut carried by and threadably coupled to the retraction cap;
• a drive screw carried by and threadably coupled to the threaded nut, the drive screw being rotatable and translatable relative to the housing to translate the therapeutic agent delivery assembly relative to the housing;
• and
• a rotary actuator configured to drive the drive screw in a first rotary direction;
• wherein the drive screw comprises a first external threaded surface, the threaded nut comprises a first internal threaded surface that threadably engages the first external threaded surface, both of the first external threaded surface and the first internal threaded surface having a first thread direction, wherein the threaded nut further comprises a second external threaded surface, the retraction cap comprises a second internal threaded surface that threadably engages the second external threaded surface, both of the second external threaded surface and the second internal threaded surface having a second thread direction opposite the first thread direction, wherein the rotary actuator is configured to drive the drive screw in the first rotary direction and first thereby translate the therapeutic agent delivery assembly from the stowed configuration to the deployed configuration due to the first thread direction, and second thereby translate the therapeutic agent delivery assembly from the deployed configuration to the retracted configuration due to the second thread direction.