Hepatic arterial infusion for treatment of liver ailments

A system for treating ailments associated with a liver of a subject, comprising:

• an implantable infusion pump;
• a catheter comprising a proximal end and a distal end, wherein the proximal end is coupled to the implantable infusion pump and the distal end is configured to be implanted in a target location of the subject;
• a processor;
• and
• a memory storing data for processing by the processor, the data, when processed, causes the processor to:
• transmit instructions to the implantable infusion pump to deliver a liquid formulation to the liver of the subject via the catheter based at least in part on the distal end being implanted in the target location, wherein the liquid formulation is configured to be delivered at a programmable flow rate for a period of time to reach a steady state concentration in the liver for providing a treatment for an ailment associated with the liver.

A system for treating ailments associated with a liver of a subject, comprising:

• an implantable infusion pump, comprising:
• a reservoir configured to house a liquid formulation;
• an outlet in fluid communication with the reservoir;
• a drive mechanism configured to control a rate at which the liquid formulation is delivered to the outlet from the reservoir;
• and
• one or more electronic components operably coupled to the drive mechanism, wherein the one or more electronic components are programmed with instructions configured to cause the liquid formulation to be delivered from the reservoir to the outlet at a programmable flow rate for a period of time to reach a steady state concentration in the liver of the subject for providing a treatment for an ailment associated with the liver.