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US 2023/0398264 A1Published application
Specialty Fibrin Product
AssigneeFibrin, LLC
InventorsMark H. Widick, Abraham Lavi
Life of this patent
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AssigneeFibrin, LLC
InventorsMark H. Widick, Abraham Lavi
Estimating the term…
The present invention is a specially prepared fibrin foam, and a method of (and equipment for) making it, which is flexible, contains either open cells, closed cells or both, and having individual cell diameters between 0.001 and 2 mm. Typical ratios of reactants, to give the desired foam characteristics, include 50 cc (45-55 cc) of whole blood (prior to separation to the plasma component) with the subsequent addition thereto of 2 ml (1.5-2.5 ml) 3% hydrogen peroxide, 5000 units (4500-5500 units) thrombin and 1 gm (0.9-1.1 g) calcium chloride in 3 cc (2-4 cc) water. The present invention also includes specialty vessels and constructs, namely, automated, or semi-automated inner containers for the non-blood reactants, and a custom outer separation vessel having a punted based with an annular base lip as well as an upper tube shape tapering inward towards its top annular opening.
A method for preparing a fibrin foam for medical use or surgical implantation to an animal or human in need thereof, comprising the steps of:
An add-on reactant chamber possessing an inner chamber and a remote-control lid thereon.
A combination system in which a reaction vessel having a frustoconical base section and a punt therein is fitted with a pre-filled chamber or syringe containing non-blood reactants.
A method of creating a fibrin foam for medical or surgical use, comprising combining a quantity of plasma with a quantity of thrombin, a quantity of calcium chloride, and an amount of entrained air adequate to prepare a foam therefrom.
Dependencies are inferred from the claim text.