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US 2023/0398186 A1Published application
HIV Treatment Compositions And Methods
AssigneeNantCell, Inc.
InventorsKayvan Niazi, Jeffrey Safrit, John H. Lee
Life of this patent
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Abstract
HIV treatment, and especially treatment of latent infected CD4 cells, can be significantly improved using a kick-and-kill approach that employs an immune stimulation component and/or HDAC inhibition as one treatment component, and that may also include a second component in which a vaccine composition, various NK cells, CAR-T cells, and/or broadly neutralizing antibodies are administered.
Claims14
A method of treating an individual that carries latent human immunodeficiency virus (HIV) infected cells, the method comprising:
- administering to the individual IL-15 or an enhanced immune stimulatory derivative thereof, and a broadly neutralizing anti-HIV antibody (bNAb).
Dependencies are inferred from the claim text.