Pharmaceutical composition comprising human interleukin 2 variant or derivative thereof and use thereof
OwnerLinmao YE, Yingfang FAN +3inventors
InventorsLinmao YE, Yingfang FAN, Yanyan SUN, Shuxiang YU, Hao CHEN
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Abstract
Provided are a pharmaceutical composition comprising a human interleukin 2 (IL-2) variant or derivative thereof and use thereof. In particular, provided are a pharmaceutical composition including a human interleukin 2 variant or derivative thereof and a pharmaceutically acceptable excipient. The pharmaceutical composition has improved high temperature, freezing and thawing, room-temperature stability, and appearance formulation reproducibility.
Claims18
A pharmaceutical composition, comprising IL-2, mannitol, trehalose and a histidine salt buffer, wherein mannitol and trehalose are in a mass ratio of 1:7 to 3:4.
Dependencies are inferred from the claim text.