Composition for enhancing immune checkpoint blockade therapy
AssigneeMeiji Co., Ltd.
InventorsHirotaka KAWANABE, Marie NAKAMURA
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Abstract
The object of the invention is to provide a composition for enhancing an immune checkpoint blockade therapy. A composition forenhancing an immune checkpoint blockade therapy, which contains an exopolysaccharide of a lactic acid bacterium is provided. Preferred examples of the lactic acid bacterium include Lactobacillus bacteria (especially Lactobacillus delbrueckii subsp. bulgaricus OLL1073 R-1).
Claims9
A composition for enhancing an immune checkpoint blockade therapy, the composition comprising an exopolysaccharide of a lactic acid bacterium.
A composition for increasing CCR6-positive CD8+T lymphocytes, the composition comprising an exopolysaccharide of a lactic acid bacterium.
A non-therapeutic method for enhancing an immune checkpoint blockade therapy, the method comprising
- making a subject ingest a composition comprising an effective amount of an exopolysaccharide of a lactic acid bacterium.
A non-therapeutic method for increasing CCR6-positive CD8+T lymphocytes in a subject, the method comprising
- making a subject ingest a composition comprising an effective amount of an exopolysaccharide of a lactic acid bacterium.
A method for increasing CCR6-positive CD8+T lymphocytes, the method comprising
- using an exopolysaccharide of a lactic acid bacterium (except for medical practices for humans).
Dependencies are inferred from the claim text.