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US 2023/0389989 A1Published application
Trajectory planning for minimally invasive therapy delivery using local mesh geometry
AssigneeClearPoint Neuro, Inc.
InventorLyubomir ZAGORCHEV
Life of this patent
Estimating the term…
Abstract
Systems and methods are provided for determining surgical trajectories (including target points and entry points) for delivering therapy to a patient's brain using a three-dimensional (3D) representation of the patient's brain (including the patient's scalp, skull, and brain) adapted from imaging data (e.g., MRI data, CT data, etc.) of the patient's brain.
Claims20
A method, comprising:
- adapting a shape-constrained deformable brain model to a head scan of a patient to generate a patient-specific 3D mesh representation of the patient's brain;
- selecting a target brain region from the patient-specific 3D mesh representation of the patient's brain;
- defining a local coordinate system for the target brain region by performing principal component analysis (PCA) on mesh vertices of the target brain region;
- defining one or more target points within the target brain region using the local coordinate system;
- determining a trajectory for the one or more target points;
- and
- determining one or more entry points for the trajectory.
4 more elements
A system comprising:
- one or more processing resources;
- and
- a non-transitory computer-readable medium, coupled to the one or more processing resources, having stored therein instructions that when executed by the one or more processing resources cause the system to perform a method comprising:
- adapting a shape-constrained deformable brain model to a head scan of a patient to generate a patient-specific 3D mesh representation of the patient's brain;
- selecting a target brain region from the patient-specific 3D mesh representation of the patient's brain;
- defining a local coordinate system for the target brain region by performing principal component analysis (PCA) on mesh vertices of the target brain region;
- defining one or more target points within the target brain region using the local coordinate system;
- determining a trajectory for the one or more target points;
- and
- determining one or more entry points for the trajectory.
7 more elements
A non-transitory computer-readable storage medium including instructions that, when executed by at least one processor of a computing system, cause the computing system to perform a method comprising:
- adapting a shape-constrained deformable brain model to a head scan of a patient's brain to generate a patient-specific 3D mesh representation of the patient's brain;
- selecting a target brain region from the patient-specific 3D mesh brain representation of the patient's brain;
- defining a local coordinate system for the target brain region by performing principal component analysis (PCA) on mesh vertices of the target brain mesh region;
- defining one or more target points within the target brain region using the local coordinate system;
- determining a trajectory for the one or more target points;
- and
- determining one or more entry points for the trajectory.
4 more elements
Dependencies are inferred from the claim text.