Genetically modified methylobacillus bacteria having improving properties
AssigneeAcies Bio d.o.o.
InventorsAleksander Johannes Kruis, David Virant, Jaka Horvat, Toni Nagode, Štefan Fujs
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AssigneeAcies Bio d.o.o.
InventorsAleksander Johannes Kruis, David Virant, Jaka Horvat, Toni Nagode, Štefan Fujs
Estimating the term…
The present invention generally relates to the biotechnology engineering, and specifically to genetically modified bacteria of the genus Methylobacillus which have improved properties making them particularly useful in large scale methanol fermentations. More specifically, the present invention provides a bacterium of the genus Methylobacillus which has been modified to have a decreased production of exopolysaccharides (EPS) compared to an otherwise identical bacterium that does not carry said modification. The present invention further provides a method for producing a biochemical compound using a genetically modified bacterium of the present invention.
A genetically engineered bacterium of the genus Methylobacillus which has been modified to inactivate an EPS gene cluster which includes genes defined by or orthologous to the open reading frames (ORFs) found in SEQ ID NO:
2-22. (canceled)
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