Oncolytic vaccinia virus deficient in large region of genes
AssigneeNational University Corporation Tottori University
InventorsTakafumi NAKAMURA, Nozomi KUWANO, Motomu NAKATAKE, Hiromichi KOUNO
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Abstract
The present invention provides a vaccinia virus which specifically grows in cancer cells and damages cancer cells and use of the virus for cancer treatment. The oncolytic vaccinia is deficient in a region consisting of 7000 to 9000 nucleotides in the genome sequence of a vaccinia virus and does not grow in normal cells, but grows specifically in cancer cells and damages cancer cells specifically.
Claims13
An oncolytic vaccinia virus which is deficient in a region consisting of 7000 to 9000 nucleotides in the genome sequence of a vaccinia virus, and does not grow in normal cells, but grows specifically in cancer cells and damages cancer cells specifically.
Dependencies are inferred from the claim text.