Sample Holder for Surface Plasmon Resonance and Plasomn-Waveguide Resonance Apparatus

A sample holder device (10) for plasmon-waveguided resonance (PWR) or surface plasmon resonance (SPR) spectroscopy, said device comprising a sample injection port (100), a prism retainer (200) and a sample compartment base (300), wherein

• said sample injection port (100) comprises:
• a top portion (104) comprising a sample injection orifice (112) for introducing a fluid sample to said sample holder device (10);
• a bottom portion (108);
• and
• a body portion (116) extending from said top portion (104) to said bottom portion (108);
• and
• a channel (120) within said body portion (116) extending from said sample injection orifice (112) to said bottom portion (108),
• and wherein said prism retainer (200) is removably attached to said sample injection port (100) and to said sample compartment base (300), wherein said prism retainer (200) comprises:
• a top portion (204);
• and
• a bottom portion (208) comprising a slotted opening (212) that is adapted to allow insertion of a prism and holding a prism in place during operation, and wherein
• said sample compartment base (300) comprises:
• a sample inet port (304) connected to a sample chamber (308), wherein said sample inlet port (304) is operatively connected to said sample injection orifice (104) of said sample injection port (100) to allow introduction of a sample into said sample chamber (308);
• a solution outlet (316A) for introducing a solution to said sample chamber (308);
• a solution inlet (316B) for removing a solution from said sample chamber (308);
• and
• a prism retainer compartment (320), wherein said prism retainer compartment (320) comprises a protuberance (324) that is adapted to hold a prism in place during operation.