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US 2023/0357433 A1Published application
Inflammatory cytokines and fatigue in subject with a complement mediated disease
AssigneeBioverativ USA Inc.
InventorsJaime Morales Arias, William E. Hobbs, Michael J. Storek, Parija S. Patel
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Abstract
Provided herein are methods for treating complement-mediated diseases and associated conditions.
Claims22
A method comprising administering to a subject an anti-C1s antibody;
- measuring a level of IL-6, and/or IL-10 in a sample from the subject;
- and optionally assessing fatigue in the subject.
(canceled)
A method comprising treating a subject with an anti-C1s antibody, wherein the subject has fatigue;
- measuring a level of IL-6, and/or IL-10 in a sample from the subject;
- and optionally assessing fatigue in the subject.
A method comprising treating a subject with an anti-C1s antibody, wherein the subject has a complement mediated disease, optionally cold agglutinin disease (CAD);
- measuring a level of IL-6, and/or IL-10 in a sample from the subject;
- and optionally assessing fatigue in the subject.
-13. (canceled)
Dependencies are inferred from the claim text.