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US 2023/0349869 A1Published application
Methods and systems for opioid detection
AssigneeNational Technology & Engineering Solutions of Sandia, LLC
InventorsMatthew W. Moorman, Joshua J. Whiting, Curtis D. Mowry
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Abstract
The present invention relates to detection systems for detecting an opioid compound by use of pyrolysis, as well as methods thereof. In particular, the systems are configured to detect the presence of a backbone fragment indicative of a class of opioid compounds, including opioid analogues.
Claims20
A detection system comprising:
- a collector comprising a substrate having surface area and a heater wiring, wherein the collector is configured to capture an analyte and to pyrolyze the analyte, and wherein the surface area is configured to thermally decompose the analyte at a first temperature to provide a plurality of backbone fragments indicative of a compound being in an opioid class and to thermally decompose the plurality of backbone fragments at a second temperature to provide a plurality of secondary fragments indicative of a structure of the compound being in the opioid class;
- an electrical control circuit connected to the heater wiring, wherein the electrical control circuit is configured to provide the first temperature from about 500° C. to about 900° C. at the surface area of the substrate and to provide the second temperature at the surface area of the substrate that is greater than the first temperature;
- a micro gas chromatograph comprising a micro gas chromatograph column and a stationary phase disposed on a surface of the micro gas chromatograph column, wherein the stationary phase is configured to interact with the plurality of backbone fragments and the plurality of secondary fragments and to elute the plurality of backbone fragments and the plurality of secondary fragments;
- a first carrier gas inlet configured to provide a first carrier gas to transport the plurality of backbone fragments and the plurality of secondary fragments from the collector to the micro gas chromatograph;
- a micro detector configured to detect the presence of the plurality of backbone fragments and the plurality of secondary fragments;
- and
- a second carrier gas inlet configured to provide a second carrier gas to transport the plurality of backbone fragments and the plurality of secondary fragments eluted from the micro gas chromatograph to the micro detector.
4 more elements
Dependencies are inferred from the claim text.