Microorganisms having capability of producing 3-hydroxypropionic acid from glucose and uses thereof
AssigneeLG Chem, Ltd.
InventorsJung Hyun JO, Min Kyung SUNG, Jae Hyung KIM
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Abstract
Provided is a microorganism having the capability of producing 3-hydroxypropionic acid from glucose and a method for producing 3-hydroxypropionic acid from glucose by using the microorganism. The microorganism can include a mutation adapted to utilize intracellularly introduced glucose in 3HP production rather than cell growth, and thus increases in 3HP productivity (3HP production capacity) can be achieved. Also provided is a method that can increase 3HP production yield by controlling the time of adding an inducer and/or kinds of an alkaline aqueous solution during culturing.
Claims18
A microorganism of the genus Escherichia, in which:
- (1) an activity of adenosyltransferase is enhanced;
- or, and
- (2) an activity of glycerol-3-phosphate dehydrogenase (GPD), glycerol-3-phosphate phosphatase (GPP), or both GDP and GPP are enhanced compared to a parent strain.
Dependencies are inferred from the claim text.