Methods for preparing pantoic acid, pantothenic acid and panthenol as well as salts thereof
AssigneeMint Bio Tech Ltd.
InventorsKechun ZHANG, Jilong WANG
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Abstract
Pantoic acid is obtained by fermenting substrate 2-hydroxy-3,3-dimethyl-4-aldehydobutyric acid by using bacteria or yeast. A microorganism is selected from bacteria or fungi. The microorganism is selected from wild or genetically engineered Escherichia coli, Bacillus, Corynebacterium, yeast or Streptomyces. Pantothenic acid is obtained by chemically reacting the pantoic acid obtained by the method described above with β-alanine. Panthenol is obtained by chemically reacting the pantoic acid obtained by the method described above with β-alaninol.
Claims11
1-14. (canceled)
A preparation method for pantoic acid, pantothenic acid and panthenol or salts thereof, comprising a step of fermenting a substrate by a microorganism, wherein the substrate comprises 2-hydroxy-3,3-dimethyl-4-oxobutanoic acid, and the 2-hydroxy-3,3-dimethyl-4-oxobutanoic acid is fermented into pantoic acid by an enzyme.
Dependencies are inferred from the claim text.