Novel erythroparvovirus associated with respiratory distress in equine
AssigneeIntervet Inc.
InventorsAd De Groof, Cornelia Maria Van Der Hoek, Martin Deijs, Cornelis Maanen Van
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Abstract
The present invention relates to a novel equine parvovirus associated with respiratory distress and recurrent laryngeal neuropathy in equine, to nucleic acid fragments and proteins of the virus and to vaccines based upon the virus, proteins and nucleic acid fragments. The invention also relates to a diagnostic test for the detection of the vims or antibodies against the virus.
Claims23
An isolated virus which is a member of the sub-family Parvovirinae of the family of the Parvoviridae, said virus being characterised in that:
- the virus is an Erythroparvovirus,
- the virus is associated with respiratory distress (RD) in equine and
- the virus has a viral genome comprising a nucleotide sequence which has a level of identity of at least 70% to the nucleotide sequence as depicted in SEQ ID NO:
- 1.
A nucleic acid fragment comprising a gene encoding the CP of claim 5, wherein the said gene has a nucleotide sequence that has a level of identity of at least 70% to the nucleotide sequence of the CP gene as depicted in SEQ ID NO:
- 2.
(canceled)
A capsid protein (CP) comprising an amino acid sequence which has a level of identity of at least 70% to the amino acid sequence according to SEQ ID NO:
- 3.
A nucleic acid fragment comprising a gene encoding the NS1 claim 8, wherein the said gene has a nucleotide sequence that has a level of identity of at least 70% to the nucleotide sequence of the NS1 gene as depicted in SEQ ID NO:
- 6.
(canceled)
A non-structural protein 1 (NS1) comprising an amino acid sequence which has a level of identity of at least 70% to the amino acid sequence according to SEQ ID NO:
- 7.
(canceled)
Dependencies are inferred from the claim text.