A self-cleaning porous layer to minimize thrombus formation on blood contacting devices

A method of preparing a self-cleaning medical device, comprising:

• obtaining a medical device having a blood contacting surface;
• fabricating within, applying to, or depositing on the blood contacting surface a porous layer or coating comprising one or more materials selected from the group consisting of synthetic biodegradable materials, synthetic nonbiodegradable materials, hybrid biomaterials including at least one synthetic biodegradable material and at least one synthetic nonbiodegradable material and biopolymers;
• and
• pre-selecting one or more properties of the porous layer or coating to control reversal fluid flow there through.

A method of reducing platelet activation and aggregation on a blood contacting surface of a medical device, comprising:

• obtaining a medical device having a blood contacting surface;
• fabricating within, applying to, or depositing on the blood contacting surface a porous layer or coating comprising one or more materials selected from the group consisting of synthetic biodegradable materials, synthetic nonbiodegradable materials, hybrid biomaterials including at least one synthetic biodegradable material and at least one synthetic nonbiodegradable material and biopolymers;
• pre-selecting one or more properties of the porous layer or coating to control reversal fluid flow there through;
• and
• pushing platelets away from the blood contact surface to reduce platelet activation and aggregation on said surface.