A combination of vaccines to prophylactically treat a pig
AssigneeIntervet Inc.
InventorsMaarten Hendrik Witvliet, Jacquelyn Horsington
Life of this patent
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Abstract
The invention pertains to a combination of a first vaccine comprising anon-replicating immunogen of porcine circovirus type 2 (PCV-2) and a non-replicating immunogen of Mycoplasma hyopneumoniae, and a second vaccine comprising a live attenuated porcine reproductive and respiratory syndrome (PRRS) virus, for use in prophylactically treating a pig against an infection with PCV-2, an infection with Mycoplasma hyopneumoniae and an infection with PRRS virus, by associated separate injection of the first vaccine and the second vaccine into a tissue of the pig at a first and a second injection site respectively, wherein the first and second injection sites are at most 5 cm apart from each other.
Claims14
(canceled)
The method of prophylactically treating of claim 12, wherein the first and second injection sites are at most 4 cm apart from each other.
The method of prophylactically treating of claim 12, wherein the associated separate injection of the first vaccine and the second vaccine occur simultaneously.
The method of prophylactically treating of claim 12, wherein the first and second vaccine through said injection are deposited at least partly into muscular tissue of the pig.
The method of prophylactically treating of claim 12, wherein the first vaccine and the second vaccine are administered by a single dose.
The method of prophylactically treating of claim 12, wherein the non-replicating immunogen of PCV2 is recombinantly expressed protein encoded by the ORF2 gene of PCV2.
The method of prophylactically treating of claim 12, wherein the non-replicating immunogen of Mycoplasma hyopneumoniae is a Mycoplasma hyopneumoniae bacterin.
A kit-of-parts for use in prophylactically treating a pig against an infection with porcine circo virus type 2, an infection with Mycoplasma hyopneumoniae and an infection with PRRS virus, comprising a first vaccine comprising a non-replicating immunogen of porcine circo virus type 2 (PCV2) and a non-replicating immunogen of Mycoplasma hyopneumoniae, and separately a second vaccine comprising a live attenuated PRRS virus;
- wherein an associated separate injection of the first vaccine and the second vaccine into a tissue of the pig at a first and a second injection site are at most 5 cm apart from each other.
A method of prophylactically treating a pig against an infection with porcine circovirus type 2 (PCV2), an infection with Mycoplasma hyopneumoniae and an infection with PRRS virus by injecting into a tissue of the pig at a first and a second injection site respectively, an associated separate injection of a first vaccine comprising a non-replicating immunogen of porcine circo virus type 2 (PCV2) and a non-replicating immunogen of Mycoplasma hyopneumoniae, and a second vaccine comprising a live attenuated porcine reproductive and respiratory syndrome (PRRS) virus;
- wherein the first and second injection sites are at most 5 cm apart from each other.
A vaccine comprising either:
- a non-replicating immunogen of porcine circo virus type 2 (PCV2) and a non-replicating immunogen of Mycoplasma hyopneumoniae, for use in prophylactically treating a pig against an infection with porcine circo virus type 2, an infection with Mycoplasma hyopneumoniae and an infection with PRRS virus, by associated separate injection of the vaccine with a second vaccine comprising a live attenuated porcine reproductive and respiratory syndrome (PRRS) virus into a tissue of the pig at a first and a second injection site respectively, or
- a live attenuated porcine reproductive and respiratory syndrome (PRRS) virus, for use in prophylactically treating an animal against an infection with porcine circo virus type 2, an infection with Mycoplasma hyopneumoniae and an infection with PRRS virus, by associated separate injection of the vaccine with a second vaccine comprising a non-replicating immunogen of porcine circo virus type 2 (PCV2) and a non-replicating immunogen of Mycoplasma hyopneumoniae into a tissue of the pig at a first and a second injection site respectively,
- wherein the first and second injection sites are at most 5 cm apart from each other.
(canceled)
Dependencies are inferred from the claim text.