Vaccination against diabetes, obesity and complications thereof
AssigneesInstitut National De La Sante Et De La Recherche Medicale (Inserm), Universite Paul Sabatier Toulouse III, Centre Hospitalier Universitaire De Toulouse
InventorsVincent BLASCO-BAQUE, Lucile GARIDOU, Remy BURCELIN
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Abstract
Vaccines for preventing or treating diabetes, obesity and complications thereof are provided. The vaccines comprise at least one active agent such as attenuated Porphyromonas gingivalis, inactivated Porphyromonas gingivalis, a subunit of Porphyromonas gingivalis, a recombinant or isolated immunogenic polypeptide or peptide from Porphyromonas gingivalis or a cDNA from Porphyromonas gingivalis.
Claims23
A method for preventing or treating periodontitis, diabetes, obesity and/or complications thereof in a subject, said method comprising administering a prophylactically or therapeutically effective amount of a vaccine composition comprising at least one prophylactically or therapeutically active agent selected from the group consisting of attenuated Porphyromonas gingivalis, inactivated Porphyromonas gingivalis, a subunit of Porphyromonas gingivalis, a recombinant or isolated immunogenic polypeptide or peptide from Porphyromonas gingivalis or a cDNA from Porphyromonas gingivalis in a subject in need thereof.
A method for preventing or treating periodontitis, diabetes, obesity and/or complications thereof in a subject, said method comprising administering a prophylactically or therapeutically effective amount of an isolated antibody having specificity for Porphyromonas gingivalis in a subject in need thereof.
Dependencies are inferred from the claim text.