Intraocular delivery of bioactive molecules using iontophoresis
AssigneeKemin Industries, Inc.
InventorsDiogo de Sousa Martins, Pierre Roy, Giovanni Cavallo, Fulvio Foschini
Life of this patent
Estimating the term…
Abstract
Iontophoresis, a minimally-invasive methodology that uses a weak electric current to enhance penetration of ionized molecules into tissues, was found to be an effective technique for the intraocular delivery of large bioactive molecules, specifically lutein.
Claims9
A method of depositing a bioactive molecule in ocular tissues, comprising the steps of formulating a liposome containing the bioactive molecule, charging an iontophoresis device with a composition of the bioactive molecule-containing liposome, applying the iontophoresis device to the eye of a subject, and operating the iontophoresis device.
A method of treating, ameliorating or preventing an ocular disease or dysfunction, comprising the steps of formulating a liposome containing the bioactive molecule, charging an iontophoresis device with a composition of the bioactive molecule-containing liposome, applying the iontophoresis device to the eye of a subject, and operating the iontophoresis device.
Dependencies are inferred from the claim text.