Acylcarnitine analysis method and acylcarnitine analysis device

A method for analyzing acylcarnitine for distinguishing different acylcarnitines having substantially same mass using a tandem mass spectrometer, the method comprising:

• a measurement step of performing a first MRM measurement for an MRM transition with maximum signal intensity and a second MRM measurement for an MRM transition different from the first MRM measurement on a specimen to acquire respective signal intensity of ions derived from a target acylcarnitine;
• and
• a processing step of distinguishing the different acylcarnitines or determining whether or not the target acylcarnitine in the specimen includes any of the different acylcarnitines, based on a confirmation ion ratio which is a ratio of a signal intensity obtained by the first MRM measurement to a signal intensity obtained by the second MRM measurement.

A method for analyzing acylcarnitine for distinguishing different acylcarnitines having substantially same mass by using a tandem mass spectrometer, the method comprising:

• a measurement step of performing MRM measurement on a specimen for specific MRM transitions different from each other determined for the different acylcarnitines to acquire respective signal intensity of ions derived from a target acylcarnitine;
• and
• a processing step of distinguishing the different acylcarnitines, or determining whether or not the target acylcarnitine in the specimen includes any of the different acylcarnitines, based on signal intensity for a specific MRM transition obtained in the measurement step.

A method for analyzing acylcarnitine for distinguishing different acylcarnitines having substantially same mass by using a tandem mass spectrometer, the method comprising:

• a measurement step of performing MRM measurement on a specimen while changing collision energy with a specific MRM transition to acquire respective signal intensity of ions derived from a target acylcarnitine;
• and
• a processing step of distinguishing the different acylcarnitines or determining whether or not the target acylcarnitine in the specimen includes any of the different acylcarnitines, based on collision energy dependency of ionic intensity obtained in the measurement step.

16-19. (canceled)