Methods, devices, and systems for treating lens protein aggregation diseases
OwnerAlan Neil Glazierinventor
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Abstract
Disclosed herein are methods, devices, and systems for treating lens protein aggregation diseases by reducing the formation of proteins responsible for crowding, compacting, and/or causing increased internal lens pressure. Specifically disclosed herein are ophthalmologic compositions comprising one or more agents that regulate water, sodium, and/or calcium ion transport and/or storage through lens fiber cell channels, and/or reduce the formation and/or production of proteins responsible for crowding, compacting, and/or causing increased internal lens pressure.
Claims26
A method for treating one or more lens aggregation diseases, the method comprising:
- administering an ophthalmologic composition into a patient's eye lens epithelium, thereby treating one or more lens aggregation diseases,
- wherein the ophthalmologic composition comprises at least one agent that at least one of:
- regulates at least one of water, sodium, calcium ion transport, and calcium ion storage through lens fiber cell channels, and
- reduces at least one of the presence and formation of proteins responsible for at least one of crowding, compacting, and causing increased internal lens pressure,
- wherein the ophthalmologic composition has a form selected from the group consisting of:
- a solution, a suspension, or combinations thereof, and
- wherein the one or more lens aggregation diseases comprises presbyopia.
A method for treating one or more lens aggregation diseases, the method comprising:
- administering an ophthalmologic composition into a patient's eye lens epithelium, thereby treating one or more lens aggregation diseases,
- wherein the ophthalmologic composition comprises at least one agent that at least one of:
- regulates at least one of water, sodium, calcium ion transport, and calcium ion storage through lens fiber cell channels, and
- reduces at least one of the presence and formation of proteins responsible for at least one of crowding, compacting, and causing increased internal lens pressure, and
- wherein the one or more lens aggregation diseases comprises presbyopia.
Dependencies are inferred from the claim text.