Reagent composition for detecting illicit drugs and sheet kit for detecting illicit drugs comprising same
AssigneeKorea Research Institute of Bioscience and Biotechnology
InventorsEun Kyung LIM, Soo Jin JANG, Seong Uk SON, Byung Hoon KANG, Tae Joon KANG, Kyu Sun LEE, Ju Yeon JUNG
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Abstract
The present disclosure provides a reagent composition for detecting illicit drugs, the composition comprising: a diacetylene derivative compound represented by chemical formula 1; and at least one compound selected from among gabazine (SR-95531), an amine group-linked diacetylene derivative represented by chemical formula 2-1, and a gabazine-linked diacetylene derivative represented by chemical formula 2-2.
Claims21
A reagent composition for detecting illicit drugs, comprising:
- a diacetylene derivative compound represented by the following Chemical Formula 1;
- and
- at least one compound selected from the group consisting of gabazine, an amine group-linked diacetylene derivative represented by the following Chemical Formula 2-1, and a gabazine-linked diacetylene derivative represented by the following Chemical Formula 2-2, and
- optionally, further comprising a polyethylene glycol-based compound;
- and a thermoplastic fluorine polymer compound:
- in Chemical Formula 1, Chemical Formula 2-1 or Chemical Formula 2-2,
- R1 is a C1-C15 alkyl group,
- R2 is a C1-C10 alkylene group, and
- R3 is -NH-C1-C6 alkylene group or a C1-C6 alkylene group.
A method for producing a sheet kit for detecting illicit drugs, comprising:
- (S1) preparing a spinning solution containing a reagent composition;
- (S2) forming a sheet by electrospinning the spinning solution;
- and
- (S3) UV-treating the sheet,
- wherein the reagent composition comprises a diacetylene derivative compound represented by the following Chemical Formula 1;
- and
- at least one compound selected from the group consisting of gabazine, an amine group-linked diacetylene derivative represented by the following Chemical Formula 2-1, and a gabazine-linked diacetylene derivative represented by the following Chemical Formula 2-2, and
- optionally, further comprising a polyethylene glycol-based compound;
- and a thermoplastic fluorine polymer compound:
- in Chemical Formula 1, Chemical Formula 2-1 or Chemical Formula 2-2,
- R1 is a C1-C15 alkyl group,
- R2 is a C1-C10 alkylene group, and
- R3 is -NH-C1-C6 alkylene group or a C1-C6 alkylene group.
(canceled)
A method for detecting illicit drugs, comprising:
- contacting a detection sample with a sheet kit containing a reagent composition,
- wherein the reagent composition comprises a diacetylene derivative compound represented by the following Chemical Formula 1;
- and
- at least one compound selected from the group consisting of gabazine, an amine group-linked diacetylene derivative represented by the following Chemical Formula 2-1, and a gabazine-linked diacetylene derivative represented by the following Chemical Formula 2-2, and
- optionally, further comprising a polyethylene glycol-based compound;
- and a thermoplastic fluorine polymer compound:
- in Chemical Formula 1, Chemical Formula 2-1 or Chemical Formula 2-2, R1 is a C1-C15 alkyl group,
- R2 is a C1-C10 alkylene group, and
- R3 is -NH-C1-C6 alkylene group or a C1-C6 alkylene group, and
- wherein the sheet kit is obtained by electrospinning of the reagent composition.
Dependencies are inferred from the claim text.