An enzyme preparation for catalyzing an epimerization reaction of a saccharide, which enzyme preparation contains a culture supernatant of a transformed cell into which any one or more of the polynucleotides (d) to (f) mentioned below has been introduced, and wherein the saccharide is selected from the group consisting of glucose, mannose, talose and galactose:
- (d) a polynucleotide consisting of a nucleotide sequence of SEQ ID NO:
- 2 or 4;
- (e) a polynucleotide that hybridizes with a complementary strand of the polynucleotide consisting of the nucleotide sequence of SEQ ID NO:
- 2 or 4 under stringent conditions, and encodes a protein having an activity for catalyzing an epimerization reaction of a saccharide;
- and
- (f) a polynucleotide having a nucleotide sequence identity of 90% or higher to the polynucleotide consisting of the nucleotide sequence of SEQ ID NO:
- 2 or 4, and encoding a protein having an activity for catalyzing an epimerization reaction of a saccharide.