Anti-tim3 single-chain antibody and use thereof in preparing medicine for treating tumor
AssigneeBeijing Neurosurgical Institute
InventorsWei ZHANG, Tao JIANG, You ZHAI, Guanzhang LI
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Abstract
The disclosure relates to an anti-TIM3 single-chain antibody. The amino acid sequence of the anti-TIM3 single-chain antibody is a sequence shown in SEQ ID NO. 1. T lymphocytes expressing the anti-TIM3 single-chain antibody can effectively kill tumor cells.
Claims14
An anti-TIM3 single-chain antibody, wherein the amino acid sequence of the anti-TIM3 single-chain antibody is a sequence shown in SEQ ID NO. 1.
A cell expressing a chimeric antigen receptor, wherein the cell expressing a chimeric antigen receptor is obtained by transfection of the expression vector according to claim by a host cell, and the chimeric antigen receptor contains an anti-TIM3 single-chain antibody, wherein the amino acid sequence of the anti-TIM3 single-chain antibody is a sequence shown in SEQ ID NO. 1.
8-9. (canceled)
Dependencies are inferred from the claim text.